
Careers
We are the innovators who are helping to find solutions to the complicated problems facing health care. United by our diverse backgrounds, we collaborate to draw upon each other’s unique skills and expertise.
We hire…
- Software Engineering & Architecture
- Test Engineering
- Technical Analysis
- Scrum
- Solutions Architecture
- Technology Services Development & Delivery Management
- Cybersecurity & Cloud Infrastructure
- Machine Learning & Data Analytics
- Data Engineering & Architecture
Our engineering team thrives on collaboration and curiosity to shift the paradigm and make an impact in the health care industry. Leveraging Agile methodology and the latest software platforms, you’ll work with product teams, clinicians, and data analysts to develop innovative health care technology. Plus, with access to leading clinical experts, you’ll gain real-world insights and feedback that enable you to iterate products to meet the needs of the end-user.
- Strategic & Technical Product Management
- Strategic & Product Design
- Business Analytics
- Portfolio Management & Development
- Investment & Transaction Management
- Program Management
- Executives in Residence
Our product team has deep knowledge of health care IT and works to create and support innovations that will impact the lives of patients in meaningful, lasting ways. You’ll work alongside clinicians, researchers, and a collaborative team of expert engineers to transform ideas into thriving business and life changing medicine.
- Investment & Transaction Management
- Business Analytics
- Portfolio Management
- Clinical & Scientific Research
- Executives in Residence
UPMC Enterprises has a robust and rapidly growing Translational Sciences focus area dedicated to investing $1 billion in life sciences startups by 2024. The team collaborates with clinicians and industry experts to rapidly bring to market new drugs, diagnostics, and devices.
- Operations
- Human Resources
- Finance & Transaction Services
- Legal
- Marketing
- Business Development
A wide range of specialties and skillsets are encompassed within the teams that make up the Business and Operations category. These experts provide critical vision and support to enhance the culture of Enterprises and boost the success of our portfolio. Whether leveraging systems and processes to help businesses run more efficiently, developing go-to-market strategies and tactics, or fostering industry relationships, you’ll be a key part of a collaborative team that is shaping the future of health care.
- Product
- Engineering & Technology Services
- Life Sciences
- Business & Operations
UPMC Enterprises Summer Associates work with mentors and gain valuable insight into all areas of our business. If you are interested in developing lasting relationships and gaining real-world exposure to the latest innovations in health care and technology, we encourage you to explore an opportunity with us.
- Product
- Engineering & Technology Services
- Life Sciences
- Business & Operations
At UPMC Enterprises, we partner with select portfolio companies to grow their teams through our robust talent acquisition system. These startups are on the cutting-edge of science and technology and are looking for a variety of expertise to take their companies to the next level.
Employee Spotlight
Want to make an impact?
Join Us“The team is always willing to lean in and do whatever needs to be done to get the job done right. There is a spirit of cooperation, curiosity, and drive for excellence that in many ways reminds me of my start-up days.”
Mary Beth Navarra-Sirio, MBA, RN
Vice President, Market Development
Digital Solutions
“I started my career in health care as a general surgeon. I am excited to now be taking a broader look at health care and help patients on a larger scale with investments in cutting-edge technologies.”
Harrison Lands, MD, MBA
Director
Translational Sciences
“Everyone on the team is eager to share their insights, lend a helping hand and engage in constructive discussions. It’s this culture of collaboration that allows us to navigate complex decisions effectively and propose well-rounded investment strategies.”
Maryam Jalal, MS
Senior Associate, Transaction Services
Business Services
Guiding Principles
Our work is shaped by specific guiding principles designed to reflect our culture and our team.
Click on each principle to learn more.
Disruptive
Change makers. We drive the required changes in the future of health care across UPMC every day.
Intense
Relentless focus. We aggressively tackle problems as a team to create life-changing products.
Collaborative
Share, build, and achieve together. We achieve our mission as one, leveraging UPMC’s collective genius and holding one another accountable.
Curious
Relentless pursuit of knowledge. We seek knowledge and perspectives through persistent exploration, questioning, and learning, in order to deploy better solutions to health care problems.
Customer-Centered
Externally focused. We strive to positively impact the necessary cultural change in health care.
Accountable
Own it and get it done. We commit to results and drive to success for ourselves, our team, our partners across UPMC, and our customers.
Life at UPMC Enterprises
Known as UPMC’s “innovation and investment arm,” Enterprises’ work supports the mission and vision of our organization as we work to further the best and brightest opportunities in health care today.
Located in the heart of downtown Pittsburgh, Enterprises embraces a modern and collaborative work environment. Our teams can work both independently and collaboratively with developers, designers, and clinicians. We pride ourselves on offering an agile atmosphere with the stability and backing of one of the nation’s largest integrated health systems.
Culture is a huge part of what sets Enterprises apart as a close-knit division. We host monthly “All Hands” meetings where we hear directly from the UPMC Enterprises leadership, invite expert guest speakers, and learn about recent team accomplishments. When teams and individuals succeed, we give them virtual “Shout-Ahts!”, entering them to win cool prizes. Through these initiatives, we stay connected among our varied teams.

The work we do here at UPMC Enterprises has the potential to revolutionize health care. Through thoughtful and diligent research, we invest in companies that we believe can positively impact patient outcomes and overcome complex industry challenges. At the core of this work is our mission and vision, supporting the patient-focused goals of the UPMC system. We are proud to shape tomorrow’s health system through clinical and technological innovation, research, and education. Through a team of talented and mission-driven innovators, we make these goals a reality.

Pittsburgh is known for its long history of pushing the boundaries of innovation and discovery, from the boom of the steel industry to life-changing medical discoveries. UPMC is grounded in this hardworking community of “Yinzers” who don’t just settle for good enough, we work toward what’s next — whether it be the latest AI innovation, a breakthrough medical discovery, or another Stanley Cup Championship.

UPMC Enterprises embraces our Pittsburgh roots as a part of the downtown scene at the US Steel Tower. Located within walking distance of PPG Paints Area (home of our beloved Pittsburgh Penguins hockey team), the Cultural District (including the beautiful Benedum Center, Byham Theatre, and Heinz Hall), and endless shopping in the Strip District. There are plenty of options for a quick lunch or a culinary experience, as well as the top hotels in the city if you’re planning a visit.
The U.S. Steel Tower houses both fun and functional amenities including newly renovated conference spaces, a lush outdoor plaza, and an on-site daycare center and fitness center.

Every investment, innovation, and business decision we make at UPMC Enterprises is guided and informed by the UPMC mission: to serve our communities by providing outstanding patient care, and shape tomorrow’s health system through clinical and technological innovation, research, and education. We are proud that our employees highly value UPMC’s organization’s commitment to a mission and vision that goes far beyond capital gains. From investing in startups that contribute to Pittsburgh’s growing innovation economy to volunteering with local organizations, we are committed to fostering a culture that gives back both in and outside of the office.